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Date: | Wed, 8 Jun 2011 10:48:34 -0400 |
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*Dissertation Defense Announcement:
To: The George Mason University Community*
*Candidate: Andrew M. Heekin
Program: PhD Bioinformatics & Computational Biology
*
*Date: Tuesday June 21, 2011
Time: 10:00 a.m.
Place: George Mason University
** Occoquan Bldg. Room 203
Prince William campus <http://www.gmu.edu/resources/visitors/findex.html>
Dissertation Chair: Dr. Patrick Gillevet
Committee members: Dr. Jason Kinser, Dr. Huzefa Rangwala
*
*Title: "Characterization of the Human Gastrointestinal Microbiome
Via Metabolic Pathway Analysis"**
*
The dissertation is on reserve in the Johnson Center Library, Fairfax campus.
The doctoral project will not be read at the meeting, but should be read in advance.
/**/All members of the George Mason University community are invited to attend.
*ABSTRACT: *
This dissertation presents a novel computational pipeline combining several
computational approaches to quantify changes, when compared to healthy controls,
that occur in the microbiome of subjects with various diseases: obesity, Cohn's Disease (CD),
and Ulcerative Colitis (UC). By analyzing samples from diseased individuals and healthy
individuals, classifiers are constructed that discriminate between a healthy gut microbiome
and a dysbiotic gut microbiome.
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