June 2011


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Wed, 8 Jun 2011 10:48:34 -0400
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"Diane St. Germain" <[log in to unmask]>
George Mason University
To: Biosciences Graduate Students <[log in to unmask]>, [log in to unmask], Anna Baranova <[log in to unmask]>, Daniel N Cox <[log in to unmask]>, Alan H Christensen <[log in to unmask]>, Chip Petricoin <[log in to unmask]>, Geraldine M Grant <[log in to unmask]>, Karl J Fryxell <[log in to unmask]>, Monique Van Hoek <[log in to unmask]>, Yuntao Wu <[log in to unmask]>, Charles L Bailey <[log in to unmask]>, Jim Willett <[log in to unmask]>, Serguei Popov <[log in to unmask]>, Lance Liotta <[log in to unmask]>, Valery Soyfer <[log in to unmask]>, Kylene Kehn-Hall <[log in to unmask]>, Fatah Kashanchi <[log in to unmask]>, Alessandra Luchini <[log in to unmask]>, Ramin M Hakami <[log in to unmask]>, Pat Gillevet <[log in to unmask]>, Pat Gillevet <[log in to unmask]> cc: "Gail L. Hodges" <[log in to unmask]>, Richard Diecchio <[log in to unmask]>, Tiffany C Sandstrum <[log in to unmask]>
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*Dissertation Defense Announcement:
To:  The George Mason University Community*

*Candidate: Andrew M. Heekin
Program: PhD Bioinformatics & Computational Biology 
*Date:   Tuesday June 21, 2011
Time:   10:00 a.m. 
Place:  George Mason University
** 	     Occoquan Bldg. Room 203
	     Prince William campus <>
Dissertation Chair: Dr. Patrick Gillevet
Committee members: Dr. Jason Kinser, Dr. Huzefa Rangwala
*Title: "Characterization of the Human Gastrointestinal Microbiome
Via Metabolic Pathway Analysis"**
The dissertation is on reserve in the Johnson Center Library, Fairfax campus.
The doctoral project will not be read at the meeting, but should be read in advance. 
/**/All members of the George Mason University community are invited to attend.

This dissertation presents a novel computational pipeline combining several
computational approaches to quantify changes, when compared to healthy controls,
that occur in the microbiome of subjects with various diseases: obesity, Cohn's Disease (CD),
and Ulcerative Colitis (UC). By analyzing samples from diseased individuals and healthy
individuals, classifiers are constructed that discriminate between a healthy gut microbiome
and a dysbiotic gut microbiome.