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Tue, 20 Nov 2012 10:38:52 -0500 |
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> Thesis Defense Announcement
> To: The George Mason University Community
>
> *Candidate: Jaimin Patel**
> Program: Master of Science in Bioinformatics & Computational Biology
> *
> *Date: Wednesday November 28, 2012
> Time: 11:00 a.m.
> Place: George Mason University
> Bull Run Hall #253
> Prince William campus <http://www.gmu.edu/resources/welcome/Directions-to-GMU.html>
>
>
> *Thesis Chair: Dr. Daniel N. Cox
>
> *Title:** "MIAMI: A GRAPHICAL INTERFACE WEB-TOOL FOR INTEGRATED MIRNA-MRNA
> INTERACTION ANALYSES IN DROSOPHILA MELANOGASTER"
>
> *
> A copy of the thesis is on reserve in the Johnson Center Library,
> Fairfax campus. The thesis will not be read at the meeting, but
> should be read in advance. All members of the George Mason University
> community are invited to attend.
>
> ABSTRACT:*
> *This thesis describes the design and implementation of a web-based
> tool -- MIAMI (miRNA and mRNA integrated analysis) -- that enables
> integrative analysis of target predictions, miRNA and gene expression
> data. MIAMI is divided into two parts: the query section and the
> analysis section. The query section allows the user to retrieve and
> browse updated miRNA-mRNA pairs predicted using a number of different
> computational algorithms such as PITA, miRanda and Target Scan as well
> as Boolean combinations of these algorithms. The analysis section
> comprises a multi-step procedure for (i) performing various
> statistical analyses of mRNA and miRNA expression data; (ii)
> visualization of networks of the highest confidence miRNA and mRNA
> interactions and; (iii) retrieval of gene, miRNA and disease-specific
> information available in several public databases via scientific
> literature text-mining.
>
> ###**
>
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