> Thesis Defense Announcement
> To:  The George Mason University Community
>
> *Candidate: Jaimin Patel**
> Program: Master of Science in Bioinformatics & Computational Biology 
> *
> *Date:   Wednesday November 28, 2012
> Time:   11:00 a.m.
> Place:  George Mason University 
> 	    Bull Run Hall #253
> 	    Prince William campus <http://www.gmu.edu/resources/welcome/Directions-to-GMU.html>
> 	
>  
> *Thesis Chair: Dr. Daniel N. Cox
>
> *Title:** "MIAMI: A GRAPHICAL INTERFACE WEB-TOOL FOR INTEGRATED MIRNA-MRNA
> INTERACTION ANALYSES IN DROSOPHILA MELANOGASTER"
>
> *
> A copy of the thesis is on reserve in the Johnson Center Library, 
> Fairfax campus.  The thesis will not be read at the meeting, but 
> should be read in advance. All members of the George Mason University 
> community are invited to attend.
>
> ABSTRACT:*
> *This thesis describes the design and implementation of a web-based 
> tool -- MIAMI (miRNA and mRNA integrated analysis) -- that enables 
> integrative analysis of target predictions, miRNA and gene expression 
> data. MIAMI is divided into two parts: the query section and the 
> analysis section. The query section allows the user to retrieve and 
> browse updated miRNA-mRNA pairs predicted using a number of different 
> computational algorithms such as PITA, miRanda and Target Scan as well 
> as Boolean combinations of these algorithms. The analysis section 
> comprises a multi-step procedure for (i) performing various 
> statistical analyses of mRNA and miRNA expression data; (ii) 
> visualization of networks of the highest confidence miRNA and mRNA 
> interactions and; (iii) retrieval of gene, miRNA and disease-specific 
> information available in several public databases via scientific 
> literature text-mining.
>
> ###**
>